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Kelsey-Seybold Clinic - Berthelsen Main Campus

Berthelsen Main Campus

2727 W. Holcombe Blvd.
Houston, TX 77025

Directions & Parking

Main Campus Construction Alert: A new expansion project is underway at Main Campus! Due to construction, parking spots in our Holcombe lot will be unavailable. We recommend patients arrive early to navigate parking. Security will be on-site to help traffic flow and our Valet Services remain available to patients at no charge.

Available Appointments at Berthelsen Main Campus

About Berthelsen Main Campus

Taking care of your health is easier than ever at our Spencer R. Berthelsen, MD, Main Campus multispecialty clinic, conveniently located just outside the Texas Medical Center and serving Rice Village and surrounding communities.

Our flagship clinic offers an on-site Kelsey Pharmacy, laboratory, X-ray, and advanced diagnostic services including CT, MRI, digital mammography with 3D breast tomosynthesis, and PET scans, so you have easy access to the high-quality care you deserve all under one roof. For your convenience, we also offer plenty of free surface-level parking and complimentary valet parking.

The Berthelsen Main Campus also houses our nationally accredited Cancer Center, Breast Diagnostic Center, and Ambulatory Surgery Center (ASC), the largest freestanding ASC in Texas. The clinic was named in honor of Kelsey-Seybold Clinic’s former Chairman of the Board and Managing Director Spencer R. Berthelsen who retired in 2017.

Welcoming New Patients and Accepting Most Health Insurance Plans

Our Berthelsen Main Campus Clinic is welcoming new patients and accepts more than 50 health insurance plans, including Aetna, Blue Cross Blue Shield, Cigna, and UnitedHealthcare. Kelsey-Seybold Clinic is also in-network with the following Medicare Advantage Plans: KelseyCare Advantage, Aetna, UnitedHealthcare and WellCare. See the complete list of 50+ Health Plans and Medicare Advantage accepted.

Care at Your Convenience

24/7 Contact Center

Call 713-442-0427 to speak to a friendly representative for appointment scheduling, assistance finding a doctor, and more.

After-Hours Nurse Hotline

Speak to a Kelsey-Seybold registered nurse for answers to health questions after regular clinic hours and on weekends and holidays by calling 713-442-0427.


Kelsey-Seybold patients have access to MyKelseyOnline, our secure patient portal that lets you send messages to your doctor, request prescription refills, and more.

MyKelsey App

Download the MyKelsey app to communicate with your doctor, schedule appointments, and more right from your mobile device using your MyKelseyOnline login.

  • MORE Specialties
  • MORE Services
  • Accreditations
  • Amenities
  • 3D Mammography (Breast Tomosynthesis)
  • Allergy Injections
  • Ambulatory Surgery Center with Endoscopy Suite
  • Audiology and Hearing Aids
  • Audiometry
  • Biopsy
  • Bone Densitometry (DEXA)
  • Bone Density Test
  • Breast Ultrasound
  • Cancer Center
  • Cardiovascular Lab
  • Colposcopy
  • CoolSculpting Fat Reduction
  • Corporate Medicine
  • CT
  • Diagnostic Radiography
  • Dietitian and Nutrition Services
  • Drug Screenings
  • Echocardiograms
  • Echocardiography (EKG)
  • EEG
  • EKG
  • EMG
  • Endoscopy
  • Executive Health Assessments
  • Exercise Prescriptions
  • Fetal Ultrasounds
  • Fluoroscopy
  • Hearing Aids
  • Hearing Test
  • Hearing Tests
  • Holter Monitoring
  • Home sleep screening
  • Immunizations
  • Infertility Referrals
  • Infusion Center
  • International Services
  • IUD Insertion/ Removal
  • Kelsey Pharmacy
  • Laboratory
  • Leeps
  • Mammography
  • MRI
  • Nexplanon
  • Non Stress Test
  • Nuclear Medicine
  • Pace Maker Clinic
  • Patient Education
  • PET CT
  • Pharmacy
  • Prolonged EEG monitoring
  • Pulmonary Function Testing
  • Spirometry
  • Stress Testing
  • Stress Testing EKG
  • Tilt-table Testing
  • Travel Medicine
  • Treadmill testing
  • Ultrasound
  • Vision Tests
  • X-ray
  • Kelsey-Seybold Clinic was named the nation’s first accredited Accountable Care Organization (ACO) in 2013 by the prestigious National Committee for Quality Assurance (NCQA).
  • The NCQA also designated Kelsey-Seybold as a Patient-Centered Medical Home (PCMH).
  • Kelsey-Seybold received the maximum three-year accreditation by the Accreditation Association for Ambulatory Health Care (AAAHC) for providing high-quality care and services consistent with AAAHC standards.
  • Flat Screen TV's
  • Free Parking
  • Free Wi-Fi
  • Luby's Cafe
  • On-site Diagnostics
  • On-site Pharmacy
  • Starbucks
  • Valet Parking
  • Vending Machines

    FOR THE SAFETY OF OUR PATIENTS AND EMPLOYEES: If you are experiencing COVID-19 symptoms (cough, fever, shortness of breath, or other upper respiratory conditions), please call our 24/7 contact center at 713-442-0000. Patients can conduct an on-demand Video Visit 7 days a week until 9 p.m. If you are having COVID-19 related symptoms, please take an at-home COVID-19 test prior to conducting a virtual or in-person visit to expedite diagnosis and treatment.

    Log in to your MyKelseyOnline account or MyChart/MyKelsey App for care.


Clinic Hours

Monday - Friday:
8 am - 5 pm

Lab Hours

Monday - Friday: 
7 am - 7 pm
8 am - 2 pm
Make a Lab Appointment

Radiology Hours

Monday - Friday: 
8 am - 6:30 pm
8:30 am - 2 pm
(limited services)

Pharmacy Hours

Monday - Friday: 
8 am - 6 pm

Directions & Parking