713-442-0427
Sheila Rastegari, DO
3102 Kirby Drive,
Houston,
TX
77098
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About the Provider
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Education & Board Certification
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Professional Associations
Professional Background
Sheila Rastegari, DO, is a double board-certified gastroenterologist and internist at Kelsey-Seybold Clinic. She attended the University of North Texas Health Science Center at Fort Worth, earning her medical degree in 2017. From there, Dr. Rastegari went on to Methodist Dallas Medical Center, completing its Internal Medicine residency program in 2020. She also completed a fellowship in Gastroenterology and Hepatology at Medical City Fort Worth in 2023. Dr. Rastegari joined Kelsey-Seybold in January 2025.
Having grown up visiting the Houston Medical Center with her mother, Dr. Rastegari was in awe of the exciting research happening there and decided then to become a physician to help people in the most direct way possible. As a gastroenterologist, she helps to prevent gastrointestinal tract cancers while also treating a wide variety of conditions, including reflux, peptic ulcer disease, inflammatory bowel disease, celiac disease, and liver disease. In addition to upper endoscopies and colonoscopies, she performs ERCP for the treatment of bile duct and gallstone-related diseases. Her clinical interests include hepatic and pancreatobiliary disease prevention and outcomes improvement — and she has particular interest in optimizing the gut microbiome, known for its role in conditions such as obesity, heart disease, and cancer.
Philosophy of Care
By getting to know her patients, Dr. Rastegari makes every effort to ensure they are well-informed and comfortable with their treatment plans. Through teamwork with her patients, she provides holistic care that incorporates both medical and lifestyle interventions.
Hobbies and Interests
Dr. Rastegari loves exploring Houston’s live music scene, trying new restaurants, and interior design. If she is not spending time with family or friends, she is probably sending them silly photos or videos of her cats. She also enjoys playing the violin and played in the Fort Worth Medical Orchestra during her time in DFW.
Awards and Publications
Research
Shah, R., Schmidt, J., John, E., Rastegari, S., Acharya, P., Kedia, P. Superior Specimen and Diagnostic Accuracy with Endoscopic Ultrasound-Guided Liver Biopsies Using 19-Gauge versus 22-Gauge Core Needles. Published in Journal of Clinical Endoscopy September 2021
Rastegari, S., Craig, C, John, E., Kedia, P., Tarnasky, P. Use of Intraductal Cholangioscopy Devices to Retrieve Migrated Pancreatic Stents. Published in Thieme Endoscopy E-videos December 2019
Brennan et al. Structural, Biochemical, and In Vivo Characterization of MtrR-Mediated Resistance to Innate Antimicrobials by the Human Pathogen Neisseria gonorrhoeae. Published in Journal of Bacteriology September 2019
Tarnasky et al. Acute Pancreatitis Task Force on Quality: Development of Quality Indicators for Acute Pancreatitis Management. Published in American Journal of Gastroenterology August 2019
Reddy, R., Rastegari, S., Kedia, P. Over-the-Scope Tissue Retraction System (TRS)-Facilitated Endoscopic Submucosal Dissection of a Large Rectal Polyp (Video Project). Published in Thieme Endoscopy E-videos May 2019
Rastegari, S., John, E., Valle, S., Acharya, P., Mantry, P. Social and Medical Determinants of NASH versus NAFLD Using Liver Histology – A Single Center Experience. Abstract presentation / American College of Gastroenterology 2019 Meeting
Rastegari, S., Brewer, C., Hoang, L. Endoscopic Management of a Surgical Clip Found Within the Common Bile Duct Following Remotely Performed Laparoscopic Cholecystectomy. Abstract presentation / American College of Gastroenterology 2019 Meeting
When communication is a bad thing: A case of cholecystocolonic fistula. Oral Presentation / Mississippi Gastroenterology Society Meeting February 2018
Makthal, N., Rastegari, S., Sanson, M., Ma, Z., Olsen, R.J., Helmann, J.D., Musser, J.M., Kumaraswami, M. Crystal structure of peroxide stress regulator PerR from Streptococcus pyogenes reveals a unique N-terminal extension that is critical for peroxide sensing and GAS virulence. Published in Journal of Biological Chemistry 2013. Oral presentations / Houston Methodist Research Center and Tri-Beta Regional Conference 2013
Education
- University of North Texas Health Science Center at Fort Worth, Texas, 2017
Internship/Residency
- Internal Medicine residency: Methodist Dallas Medical Center Internal Medicine Residency Program, 2020; Gastroenterology and Hepatology fellowship: Medical City Fort Worth, 2023
Board Certifications
- American Board of Internal Medicine - Gastroenterology
- American Board of Internal Medicine - Internal Medicine
