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Portrait of Sheila Rastegari, DO, Gastroenterology specialist at Kelsey-Seybold Clinic.
My Video Profile

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  • About the Provider
  • Education & Board Certification
  • Professional Associations

Professional Background

Sheila Rastegari, DO, is a board-certified gastroenterologist at Kelsey-Seybold Clinic. She attended the University of North Texas Health Science Center at Fort Worth, earning her medical degree in 2017. From there, Dr. Rastegari went on to Methodist Dallas Medical Center, completing her Internal Medicine residency in 2020. She then completed her fellowship in Gastroenterology and Hepatology in 2023 at Medical City Fort Worth, where she served as Chief Fellow. Dr. Rastegari joined Kelsey-Seybold in January 2025.

As a gastroenterologist, she helps to prevent gastrointestinal tract cancers while also treating a wide variety of conditions, including reflux, peptic ulcer disease, inflammatory bowel disease, celiac disease, and liver disease. Her clinical interests include hepatic and pancreatobiliary disease prevention and outcome improvement, as well as optimization of the gut microbiome.

Philosophy of Care

By getting to know her patients, Dr. Rastegari makes every effort to ensure they are well-informed and comfortable with their treatment plans. Through teamwork with her patients, she provides holistic care that incorporates both medical and lifestyle interventions.

Hobbies and Interests

Dr. Rastegari loves spending time with family and friends, exploring Houston’s live music scene, and interior design. She also enjoys playing the violin and played in the Fort Worth Medical Orchestra during her time in DFW.

Awards and Publications

Research

Shah, R., Schmidt, J., John, E., Rastegari, S., Acharya, P., Kedia, P. Superior Specimen and Diagnostic Accuracy with Endoscopic Ultrasound-Guided Liver Biopsies Using 19-Gauge versus 22-Gauge Core Needles. Published in Journal of Clinical Endoscopy September 2021

Rastegari, S., Craig, C, John, E., Kedia, P., Tarnasky, P. Use of Intraductal Cholangioscopy Devices to Retrieve Migrated Pancreatic Stents. Published in Thieme Endoscopy E-videos December 2019

Brennan et al. Structural, Biochemical, and In Vivo Characterization of MtrR-Mediated Resistance to Innate Antimicrobials by the Human Pathogen Neisseria gonorrhoeae. Published in Journal of Bacteriology September 2019

Tarnasky et al. Acute Pancreatitis Task Force on Quality: Development of Quality Indicators for Acute Pancreatitis Management. Published in American Journal of Gastroenterology August 2019

Reddy, R., Rastegari, S., Kedia, P. Over-the-Scope Tissue Retraction System (TRS)-Facilitated Endoscopic Submucosal Dissection of a Large Rectal Polyp (Video Project). Published in Thieme Endoscopy E-videos May 2019

Rastegari, S., John, E., Valle, S., Acharya, P., Mantry, P. Social and Medical Determinants of NASH versus NAFLD Using Liver Histology – A Single Center Experience. Abstract presentation / American College of Gastroenterology 2019 Meeting

Rastegari, S., Brewer, C., Hoang, L. Endoscopic Management of a Surgical Clip Found Within the Common Bile Duct Following Remotely Performed Laparoscopic Cholecystectomy. Abstract presentation / American College of Gastroenterology 2019 Meeting

When communication is a bad thing: A case of cholecystocolonic fistula. Oral Presentation / Mississippi Gastroenterology Society Meeting February 2018

Makthal, N., Rastegari, S., Sanson, M., Ma, Z., Olsen, R.J., Helmann, J.D., Musser, J.M., Kumaraswami, M. Crystal structure of peroxide stress regulator PerR from Streptococcus pyogenes reveals a unique N-terminal extension that is critical for peroxide sensing and GAS virulence. Published in Journal of Biological Chemistry 2013. Oral presentations / Houston Methodist Research Center and Tri-Beta Regional Conference 2013

Joined Kelsey-Seybold: January 2025

Education

  • University of North Texas Health Science Center at Fort Worth, Texas, 2017

Internship/Residency

  • Internal Medicine residency: Methodist Dallas Medical Center Internal Medicine Residency Program, 2020; Gastroenterology and Hepatology fellowship: Medical City Fort Worth, 2023

Board Certifications

  • American Board of Internal Medicine - Gastroenterology
  • American Board of Internal Medicine - Internal Medicine
Dr. Rastegari is a member of the American College of Gastroenterology and American Society for Gastrointestinal Endoscopy.

Locations

Upper Kirby Clinic

3102 Kirby Drive,
Houston, TX 77098

Get Directions 346-674-2300

Hospital Affiliations

  • St. Luke's Health - Baylor St. Luke's Medical Center

Accepted Insurance