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Portrait of Alexander Metoxen, MD, Orthopedics and Orthopedic Surgery specialist at Kelsey-Seybold Clinic.
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Alexander Metoxen, MD

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  • About the Provider
  • Education & Board Certification
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Alexander Metoxen, MD, is a fellowship-trained orthopedic surgeon specializing in hip and knee replacement. He earned his Doctor of Medicine in 2016 from the University of Colorado School of Medicine in Aurora and completed his Orthopedic Surgery residency in 2021 at the University of Missouri – Kansas City. In 2022, he completed his Adult Reconstructive Orthopedics fellowship at Baylor College of Medicine in Houston, Texas.

Dr. Metoxen has coauthored numerous scientific papers and researched various orthopedics aspects. He also has presented at research symposiums and grand rounds on the evaluation and treatment of orthopedic diseases and joint replacement surgery.

He joined Kelsey Seybold in August of 2022.

Joined Kelsey-Seybold: August 2022

Awards & Publications


  • Rex L. Diveley Award for Outstanding Orthopedic Surgery Resident, 2021
  • Third Place Award for American IPA in Peak-to-Peak Pro-Am homebrew competition, 2016
  • Western Medical Student Research Forum Subspecialty, Award, 2014
  • University of Colorado Student Research Forum Poster Award, 2013
  • University of Colorado School of Medicine Presidential Scholarship, 2012 – 2016
  • College of Science Summer Undergraduate Research Fellowship, 2011
  • Braco Award for Research Excellence in Cell Biology, 2010
  • Achieved Rank of Eagle Scout in the Boy Scouts of America, 2008


  • Metoxen AJ, Leming MT, Hu X, Whaley MA, O’Tousa JE. Light-driven processes control both rhodopsin maturation and recycling in mosquito photoreceptors. Journal of Neuroscience. 2016
  • Seedorf, G, Metoxen AJ, Rock R, Markham N, Ryan S, Vu T, and Abman SH. Hepatocyte growth factor as a downstream mediator of vascular endothelial growth factor-dependent preservation of growth in the developing lung. Am J Physiol Lung Cell Mol Physiol. 2016.
  • Moon, YM, Metoxen AJ, Leming MT, Whaley MA, and O’Tousa JE. Rhodopsin management during the light-dark cycle of Anophales gambiae mosquitoes. Journal of Insect Physiology. 2014.
  • Metoxen AJ, Seedorf G and Abman S. Hepatocyte growth factor stimulates fetal sheep alveolar type II cell and endothelial cell growth and improves lung structure in experimental bronchopulmonary dysplasia [Abstract]. Journal of Investigative Medicine. 2014.
  • Hu, X, Leming MT, Metoxen AJ, Whaley MA, and O'Tousa JE. Light-mediated control of rhodopsin movement in mosquito photoreceptors. Journal of Neuroscience. 2012.


  • Baylor College of Medicine Arthroplasty Conference Presentation, 2021
    • Dual-Mobility for Instability in Total Hip Arthroplasty
  • UMKC Orthopedic Surgery Grand Rounds Presentations
    • Lisfranc Injuries – ORIF versus Arthrodesis, 2021
    • Robotics in Total Knee Arthroplasty, 2020
    • The History of Total Hip Arthroplasty Design, 2019
    • Slipped Capital Femoral Epiphysis – Evaluation and Treatment, 2018
    • Legg-Calvé-Perthes Disease – Evaluation and Treatment, 2017
  • Research Presentations
    • Risk Factors of Avascular Necrosis in Unstable Slipped Capital Femoral Epiphysis, 2021
    • Western Medical Student Research Forum – Carmel, Calif., 2014
    • University of Colorado Pediatrics Department Research Forum, 2014
    • University of Colorado Student Research Forum, 2013
    • University of Notre Dame College of Science Joint Annual Meeting, 2011 and 2012


  • Orthopedic Surgery Research Kansas City, Mo., 2018 – 2021
    • Studied the risk factors of avascular necrosis and other complications in unstable slipped capital femoral epiphysis in children
    • Manuscript planned for submission for peer-reviewed publication in near future
  • University of Colorado School of Medicine Research Track Aurora, Colo., 2012 – 2016
    • Researched bronchopulmonary dysplasia and the role of hepatocyte growth factor in disease pathogenesis and as a potential therapeutic agent
    • Presented project at Western Medical Student Research Forum in Carmel, Calif.
  • Research Technician R2 Diagnostics/Enzyme Research Laboratories, 2010 – 2012
    • Researched and developed clinical assays for diagnostic testing in the healthcare setting
    • Independently designed novel experimental techniques and protocols for research
  • Undergraduate Research, O’Tousa Lab, 2010 – 2012
    • Characterized opsin 1 visual protein in Aedes aegypti photoreceptor cells
    • Studied expression and localization of opsin 1 under light and dark conditions
    • Duffield Lab 2010 Genotyped knockout mice using PCR amplification for experimental use
  • Research Associate National Jewish Health, Colo., 2009
    • Studied the fibrin-dependent neutrophil extracellular trap (NET) immune response
    • Compared NET formation in response to bacteria and aluminum adjuvants from vaccines

Hobbies & Interests

Dr. Metoxen enjoys playing piano, cooking, traveling, homebrewing beer, and playing with his dogs.

Fun Facts

The best advice Dr. Metoxen has received is “Question everything – refuse to accept tradition or dogma and strive to research and discover the answer yourself.”

The most interesting place he has visited is Rome, Italy, where he studied during undergraduate training.

Not everyone knows this about Dr. Metoxen, but his last name comes from his Native American ancestry. Donuts are his guilty pleasure.

As a child, Dr. Metoxen wanted to be a fighter pilot in the Air Force because he enjoyed flying and adventure.

Medical School

  • University of Colorado School of Medicine, Aurora, 2016


  • Orthopedic Residency: University of Missouri, Kansas City, 2021; Adult Reconstructive Orthopedics Fellowship: Baylor College of Medicine, Houston, Texas, 2022
Dr. Metoxen is a member of the American Association of Hip and Knee Surgeries and the American Academy of Orthopedic Surgeries.


Berthelsen Main Campus

2727 W. Holcombe Blvd.,
Houston, TX 77025

Get Directions 713-442-0000

Hospital Affiliations

  • HCA Houston Healthcare - Clear Lake
  • Bay Area Surgicare Center
  • St. Luke's Health - Baylor St. Luke's Medical Center

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