Alexander Ou, MD

Kelsey-Seybold Medical Group Provider
PointerLanguage(s): English, Mandarin, Spanish
2515 Business Center Drive,
Pearland,
TX
77584
Joined Kelsey-Seybold: August 2022
Ways to Schedule an Appointment
My Video Profile
My Biography
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Professional Background
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Professional Associations
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Hobbies and Interests
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Awards & Publications
Dr. Alexander Ou is a board-certified neurologist with fellowship training in Neuro-Oncology. He earned his Doctor of Medicine degree in 2015 at New York Medical College in Valhalla and completed his residency in 2019 at Stony Brook University Hospital in New York. Dr. Ou did his fellowship training in Neuro-Oncology in 2021 at The University of Texas MD Anderson Cancer Center in Houston.
He has conducted various neurology and neurology-oncology research projects in association with the National Heart Lung and Blood Institute, The University of Texas MD Anderson Cancer Center, and the Dana-Farber Cancer Institute. In addition, Dr. Ou is a published co-author of multiple scientific papers, abstracts, and book chapters.
Dr. Ou cared for patients at HCA Houston Healthcare prior to joining Kelsey Seybold in August 2022.
Dr. Ou enjoys cooking, traveling, exploring new restaurants, board sports, and spending time with family.
Fun Facts
As a child, Dr. Ou wanted to be a pyrotechnic chemist because he loved the idea of science and explosions. He was wisely steered toward a safer profession.
Awards
- William James Miller Endowed Fellowship Award, 2019 – 2020: Awarded for study of “Quality of End-of-Life Care in Patients with High-Grade Glioma,” under research mentor Dr. Rebecca Harrison. - Funded through the generous support of the Miller family, the Department of Neuro-Oncology, and Dr. Victor Levin
- Alpha Omega Alpha Honor Medical Society, Iota Chapter of New York Medical College, 2014: Elected to junior AOA for academic and clinical achievement
- Dana-Farber Cancer Institute Departmental Innovator Award, 2008: Awarded for intellectual and technical contributions to several ongoing projects in lab of Dr. Benz and Dr. Haung
- Dartmouth College Presidential Scholar Research Assistantship, 2006: Awarded to sophomore undergraduate students for demonstrated academic achievement
Publications and Presentations
- Ou, A., Ott, M., Fang, D., & Heimberger, A. B. (2021). The Role and Therapeutic Targeting of JAK/STAT Signaling in Glioblastoma. Cancers, 13(3), 437. https://doi.org/10.3390/cancers13030437
- Ou, A., Yung, W., & Majd, N. (2020). Molecular Mechanisms of Treatment Resistance in Glioblastoma. International journal of molecular sciences, 22(1), 351. https://doi.org/10.3390/ijms22010351
- Ou, A., Sumrall, A., Phuphanich, S., Spetzler, D., Gatalica, Z., Xiu, J., Michelhaugh, S., Brenner, A., Pandey, M., Kesari, S., Korn, W. M., Mittal, S., Westin, J., & Heimberger, A. B. (2020). Primary CNS lymphoma commonly expresses immune response biomarkers. Neuro-oncology advances, 2(1), vdaa018. https://doi.org/10.1093/noajnl/vdaa018
- Huang, S. C., Liang, J. Y., Vu, L. V., Yu, F. H., Ou, A.C., Ou, J. P., Zhang, H. S., Burnett, K. M., & Benz, E. J., Jr (2020). Epithelial-specific isoforms of protein 4.1R promote adherens junction assembly in maturing epithelia. The Journal of biological chemistry, 295(1), 191–211. https://doi.org/10.1074/jbc.RA119.009650
- Huang, S. C., Zhang, H. S., Yu, B., McMahon, E., Nguyen, D. T., Yu, F. H., Ou, A.C., Ou, J. P., & Benz, E. J., Jr (2017). Protein 4.1R Exon 16 3' Splice Site Activation Requires Coordination among TIA1, Pcbp1, and RBM39 during Terminal Erythropoiesis. Molecular and cellular biology, 37(9), e00446-16. https://doi.org/10.1128/MCB.00446-16
- Huang, S. C., Ou, A.C., Park, J., Yu, F., Yu, B., Lee, A., Yang, G., Zhou, A., & Benz, E. J., Jr (2012). RBFOX2 promotes protein 4.1R exon 16 selection via U1 snRNP recruitment. Molecular and cellular biology, 32(2), 513–526. https://doi.org/10.1128/MCB.06423-11
- Huang, S. C., Cho, A., Norton, S., Liu, E. S., Park, J., Zhou, A., Munagala, I. D., Ou, A.C., Yang, G., Wickrema, A., Tang, T. K., & Benz, E. J., Jr (2009). Coupled transcription-splicing regulation of mutually exclusive splicing events at the 5' exons of protein 4.1R gene. Blood, 114(19), 4233–4242. https://doi.org/10.1182/blood-2009-02-206219
- Zhou, A., Ou, A.C., Cho, A., Benz, E. J., Jr, & Huang, S. C. (2008). Novel splicing factor RBM25 modulates Bcl-x pre mRNA 5' splice site selection. Molecular and cellular biology, 28(19), 5924–5936. https://doi.org/10.1128/MCB.00560- 08
Abstracts
- Ou AC, Soomro Z, Bornstein C, Alfaro-Munoz K, de Groot J, Majd N. The Risk and Burden of Thromboembolic and Hemorrhagic Events in Patients with Malignant Glioma Receiving Bevacizumab. Accepted at Society for Neuro-Oncology (SNO) 2021 meeting.
- Ou AC, Kebriaei P, Tummala S. An Unusual Presentation of Radiation Necrosis in the Brainstem. Presented at American Academy of Neurology (AAN) 2021 Annual Meeting.
- Ou AC, Harrison RA, Liu D, Naqvi M, Naqvi SM, O’Brien BJ, Weathers SP, de Groot JF, Bruera E. Quality of End-of Life Care in Patients with High-Grade Glioma. Presented at Society for Neuro-Oncology (SNO) 2020 meeting
- Garrido-Sanabria E, Jones RA, Ou AC, Syritsyna O, Kowalska A, Coyle PK, Peyster R. A Case of Anti-Aquaporin-4 Antibody-Positive NMOSD Associated with Primary CNS Lymphoma. Presented at American Academy of Neurology (AAN) 2019 Annual Meeting.
- Ou AC, Heslin R, Kowalska A. Rare Malignant Transformation of an Epidermoid Cyst. Presented at American Academy of Neurology (AAN) 2018 Annual Meeting.
- Shehzad, U, Ou AC, Kowalska A. Rare Presentation of Malignant Myxomatous Aneurysms with PRKAR1A Gene Mutation. Presented at American Academy of Neurology (AAN) 2018 Annual Meeting.
Book Chapters
- Ou, AC, Weathers S. “Treatment and Prevention of Venous Thrombo-Embolism.” Brain Tumors: A Pocket Guide – Submitted
- Ou AC, O’Brien BJ. “Neurologic Complications of Breast Cancer.” Newton/Neurological Complications of Systemic Cancer and Antineoplastic Therapy, Second Edition. – Accepted
- 07/2019-06/2021 UCNS Review, M&M Conference, Neuro-Oncology Core Curriculum – prepared and gave lectures in fundamental topics in clinical neuro-oncology, as well as instructive clinical cases
Research
- 01/2020 – 06/2021 University of Texas MD Anderson, Dr. Nazanin Majd - Studying role of anticoagulation in high-risk glioma patients
- 08/2019 – 06/2021 University of Texas MD Anderson, Dr. Rebecca Harrison - Studying end-of-life quality of life measures in patients with high-grade gliomas
- 07/2017 – 06/2019 Stony Brook University Hospital, Dr. Samuel Ryu - Studied role of inflammation in gliomas
- 06/2012 – 09/2012 National Heart Lung and Blood Institute, Center for Molecular Medicine, Dr. Haiming Cao; - Investigated role of novel long non-coding RNAs in metabolic disease pathways
- 07/2007 – 07/2010 Dana-Farber Cancer Institute, Department of Medical Oncology, Dr. Edward Benz and Dr. Shu-Ching Huang - Studied changes in protein 4.1R isoform expression during erythrocyte differentiation and alternative splicing control of genes involved in apoptosis
- 06/2006 – 09/2006 Dartmouth College, Thayer School of Engineering, Dr. Brian Pogue - Studied near-infrared imaging and use of photosensitizers in cancer therapeutics - Designed and performed experiments and analyzed results
- 01/2005 – 06/2005 Dartmouth College, Dartmouth Medical School, Dr. William North – Studied NMDA receptor expression in small-cell lung cancer
Accepted Insurance
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AmeriBen TPA
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Cigna Plans
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- Cigna KelseyCare
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Blue Cross Blue Shield Plans
Blue Cross Blue Shield
The specific BCBSTX PPO and HMO plans in which Kelsey-Seybold participates are:
- Anthem BCBS PPO
- Blue Access Choice PPO
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- Blue Card PPO
- Blue Essentials HMO Click here to learn more about selecting a Kelsey Primary Care Physician
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Kelsey-Seybold will not participate in the following BCBSTX plans: Blue Premier, Blue High-Performance network, Marketplace plans: My Blue Health, and Blue Advantage HMO, or any BCBSTX Medicare products. View FAQ (pdf)
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Humana Plans
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Non-Medicare Advantage
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Medicare Advantage
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Aetna Plans
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Aetna PPO, POS, and EPO Plans
Kelsey-Seybold Clinic is an in-network provider for most Aetna PPO, POS, and EPO plans*, including:
- Aetna Select
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Aetna CVS Health Marketplace Plans
Effective January 1, 2023
- Bronze S
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*All Houston area Aetna CVS Health plans are accepted at Kelsey-Seybold Clinic*
*Kelsey-Seybold does not participate in any commercial Aetna HMO and HNO plans, including Aetna QPOS.
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UnitedHealthcare Plans
UnitedHealthcare (UHC)
- UnitedHealthcare Charter
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- UnitedHealthcare Choice
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- UnitedHealthcare Navigate
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- UnitedHealthcare Navigate Plus
- Note: A Kelsey-Seybold PCP is required to schedule a primary care appointment. Please contact United Healthcare Navigate Plus at the phone number on the back of your member ID card or go online to the United Healthcare member portal to select a Kelsey-Seybold PCP prior to your appointment.
- UnitedHealthcare NexusACO-R
- Note: A Kelsey-Seybold PCP is required to schedule a primary care appointment. Please contact United Healthcare NexusACO at the phone number on the back of your member ID card or go online to the United Healthcare member portal to select a Kelsey-Seybold PCP prior to your appointment.
- UnitedHealthcare NexusACO (OAP and OA)
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- UnitedHealthcare Select
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Other Plans
Allied Benefit Systems/NGBS
Federal Employee Health Benefits (FEHB)
- APWU Health Plan Nationwide – CDHP with UnitedHealthcare PPO
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- GEHA Benefit Plan Nationwide – High & Standard Options with UnitedHealthcare Choice Plus
- NALC Nationwide with Cigna OAP
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Great West Healthcare (also known as Cigna-GWH)
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HealthSmart PPO
Medicare
Kelsey-Seybold Clinic accepts the following Medicare Advantage Plans: KelseyCare Advantage, Aetna Medicare Advantage, WellCare TexanPlus, Humana Medicare and select UnitedHealthcare plans. Effective January 1, 2009, Kelsey-Seybold Clinic does not accept patients with traditional Medicare.
MultiPlan PPO
Private Healthcare Systems PPO (PHCS)
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Kelsey Plans
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When you select a Kelsey Plan, you’re choosing the doctors at Kelsey-Seybold Clinic to deliver and coordinate your care. Learn more here.
KelseyCare Advantage
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Kelsey-Seybold does not participate in Aetna HMO and HNO plans, including Aetna QPOS.
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Education and Board Certifications
Medical School
- New York Medical College, Valhalla, NY, 2015
Internship/Residency
- Stony Brook University Hospital, Stony Brook, NY, 2019; Fellowship: The University of Texas MD Anderson Cancer Center, Houston, Neuro-Oncology, 2021
Board Certifications
- American Board of Psychiatry and Neurology - Neurology